What is food mineral?

Minerals are inorganic elements that originate in the earth and cannot be made in the body. They play important roles in various bodily functions and are necessary to sustain life and maintain optimal health, and thus are essential nutrients.

Tuesday, July 13, 2021

Hemochromatosis

Hemochromatosis is defined as a metabolic disorder affecting iron absorption, and resulting in the accumulation of excess iron in the body’s organs. Normally, iron absorption is tightly regulated because the body is incapable of excreting excess iron. Hemochromatosis occurs when there are high pathologic levels of iron accumulation in the body.

Iron is important because it is part of hemoglobin, a molecule in the blood that transports oxygen from the lungs to all body tissues. Normal iron absorption occurs in the proximal small intestine at a rate of 1-2 mg per day. In people with hereditary hemochromatosis, this absorption rate can reach 4–5 mg per day with progressive accumulation to 15–40 grams of iron in the body.

Humans have no physiologic pathway to excrete iron. Therefore, iron can accumulate in any body tissue, although depositions are most common in the liver, thyroid, heart, pancreas, gonads, hypothalamus and joints. Hemochromatosis causes or exacerbates arthritis, diabetes, impotence, heart failure, cirrhosis of the liver and liver cancer.

Excessive alcohol intake and viral hepatitis accelerate the pathology associated with hemochromatosis, especially with respect to liver and pancreatic toxicity. Diabetes is the primary manifestation of pancreatic iron deposition. The incidence of diabetes is approximately 50% in symptomatic patients, and the risk is increased in heterozygotes for hereditary hemochromatosis.

The three types of hemochromatosis are primary hemochromatosis, also called hereditary hemochromatosis; secondary hemochromatosis; and neonatal hemochromatosis.

The most common cause of secondary hemochromatosis is frequent blood transfusions in people with severe anemia.
Hemochromatosis

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