What is food mineral?

Minerals are inorganic elements that originate in the earth and cannot be made in the body. They play important roles in various bodily functions and are necessary to sustain life and maintain optimal health, and thus are essential nutrients.

Thursday, June 29, 2017

Zinc finger

Mineral zinc perhaps the most ubiquitous and versatile of all metal cofactors. Zinc- binding proteins that engage DNA, the so called zinc finger proteins, attest to the versatility of zinc in biological systems.

Zinc fingers may have evolved originally from peptides, which maintained a simple ββα structure independently of zinc.
Zinc finger ribbon structure
Zinc fingers are abundant in nature and the huge variety found in various organisms, from yeast to human, may in part be due to their modular nature. Approximately 3% of the genome of mammals codes for zinc finger protein.

In zinc finger proteins, Zn2+ contributes of the stability of the loop structure that contracts the major and minor grooves of DNA.

The majority of zinc fingers fall into three fold groups: the C2H2-like zinc finger, the treble clef zinc finger and the zinc ribbon.
Zinc finger
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